休时间有氧体力活动时间与明显的耐治疗高血压的关联:基于NHANES数据库的研究
Wanling Huang1, Dongqin Lai1, Meie Zeng1
1General Practice Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan City, Fujian Province, 364000, China.
Biology of sport
|October 6, 2025
概括
参与休时间有氧体力活动 (LTAPA) 与明显耐治疗高血压 (aTRH) 的风险降低以及高血压患者的死亡率降低有关. 增加LTAPA对不饮酒的女性最有好处.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 运动科学 运动科学
背景情况:
- 显而易见的耐治疗高血压 (aTRH) 影响了大量高血压患者,增加了他们患心血管事件和死亡的风险.
- 休时间有氧体力活动 (LTAPA) 是一种可修改的生活方式因素,对心血管健康有着已知的好处.
- LTAPA与aTRH发生率和结果之间的特定关联仍然是一个需要进一步研究的领域.
研究的目的:
- 研究美国成年人休时间有氧体力活动 (LTAPA) 时间和明显的耐治疗高血压 (aTRH) 之间的关联.
- 检查LTAPA与被诊断患有aTRH的患者全因死亡率之间的关系.
- 确定可能从高血压管理中增加体力活动中受益最多的潜在人口亚组.
主要方法:
- 来自国家健康和营养检查调查 (NHANES) 数据库 (2007-2018) 数据的横截面分析.
- 包括6,705名高血压患者,分为aTRH (413) 和非aTRH (6,292) 组.
- 使用权重后勤和考克斯回归模型,分别评估LTAPA与aTRH风险和全因死亡率的关联. 还进行了卡普兰-梅尔生存分析.
主要成果:
- 与非aTRH组相比,aTRH组的每周LTAPA时间明显低于非aTRH组 (76.15分 vs 103.16分钟,p=0.016).
- 增加的LTAPA与发展aTRH的风险降低有关 (OR=0.939,p=0.045),特别是在不饮酒的女性中.
- 较高的LTAPA与aTRH患者全因死亡风险较低 (OR=0.900,p=0.010) 和延长生存时间显著相关.
结论:
- 在休时间增加有氧体力活动与明显抗治疗高血压的发病率降低以及高血压患者全因死亡率降低有关.
- 性别特定的运动策略,特别是对于不喝酒的女性来说,可能有助于管理aTRH.
- 促进LTAPA可以是一个有价值的非药物干预措施,以改善高血压和aTRH患者的治疗结果.
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