在活性流体系统的法化中,IOP-20和IOP-50之间的术后结果的比较:随机单盲试验
Chandrashekhar M Wavikar1, Mamta N Tanna1, Gargi C Wavikar2
1Department of Ophthalmology, Wavikars Eye Hospital and Wavikar Eye Institute, Thane, Maharashtra, India.
Clinical ophthalmology (Auckland, N.Z.)
|October 6, 2025
概括
使用CENTURION视觉系统与ACTIVE SENTRY在20mmHg眼内压力 (IOP) 的白内障手术需要比50mmHg更少的激增缓解. 这表明20mmHg提供了一个稳定的外科环境.
科学领域:
- 眼科医生 眼科 眼科
- 手术技术 手术技术
- 角质科学 角质科学
背景情况:
- 白内障手术是恢复视力的常见手术.
- 在手术期间保持稳定的眼内压 (IOP) 对患者的治疗结果至关重要.
- 具有ACTIVE SENTRY的Centurion视觉系统为白内障手术提供了先进的流体.
研究的目的:
- 为了比较中枢角膜厚度 (CCT),缓解事件,术后视力和白内障手术中的并发症.
- 评估两种眼内压 (IOP) 设置 (20 mmHg vs. 50 mmHg) 的安全性和有效性,使用带有ACTIVE SENTRY的Centurion视觉系统.
- 确定IOP对手术稳定性和患者结果的影响.
主要方法:
- 一项前性,随机的,单盲的干预研究,涉及107只眼睛.
- 患者被分配到IOP-20组 (n=55) 或IOP-50组 (n=52).
- 使用CENTURION视觉系统与ACTIVE SENTRY进行了化,IOP设置为20mmHg或50mmHg.
主要成果:
- 在IOP-20和IOP-50组之间,在基线或手术后的中枢角膜厚度 (CCT) 中没有观察到统计学上显著的差异.
- 手术后90天内皮细胞密度 (ECD) 在两组之间没有显著差异.
- 与IOP-20组相比,IOP-50组中的眼睛比例显著更高 (77%) 需要积极的激增缓解 (22%) (p<0.001).
结论:
- 在20 mmHg IOP下使用活性流体系统的法乳化提供了安全稳定的外科环境.
- 较低的IOP设置 (20 mmHg) 可以减少在白内障手术期间进行手术内激增缓解的需要.
- 带有ACTIVE SENTRY的Centurion视觉系统有效地管理白内障手术期间的内压,其20 mmHg可提供增强的稳定性.
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