预查饮食模式与退伍军人纵向结肠镜检查结果之间的关联
April R Williams1, Thomas S Redding2, Brian A Sullivan2,3
1Veterans Affairs Boston Healthcare System, Massachusetts.
包括地中海饮食和DASH在内的健康饮食模式与在接受结肠直肠癌查的美国退伍军人中,晚期瘤的几率降低有关. 这些发现支持癌症预防策略中的饮食指导.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 预防医学 预防医学
背景情况:
- 饮食习惯显著影响长期健康结果,包括癌症风险.
- 结肠直肠癌 (CRC) 仍然是一个重大的健康问题,特别是在美国退伍军人等特定的人口群体中.
- 包括饮食在内的生活方式建议越来越多地被纳入CRC查计划.
研究的目的:
- 研究坚持特定饮食模式与美国退伍军人结直肠瘤风险之间的关联.
- 在CRC查协议中提供基于证据的见解,用于患者和临床医生讨论CRC查协议中的生活方式修改.
主要方法:
- 在1994年至1997年期间接受查结肠镜检查的无症状的美国退伍军人 (年龄在50-75岁) 队列被跟踪到2009年.
- 通过使用食物频率问卷评估饮食摄入量,计算健康饮食指数 (HEI),地中海饮食 (MD) 和DASH饮食的得分.
- 多项逻辑回归模型分析了饮食模式得分与最重要的结肠镜检查结果 (MSCFs) 之间的关联,包括先进瘤 (AN).
主要成果:
- 较高的HEI,MD和DASH饮食模式的坚持显示,与没有瘤相比,先进瘤的调整几率比率 (aOR) 类似或更低.
- 具体来说,较高的MD和DASH得分与降低AN的几率有关.
- 在这些饮食模式中增加谷物消费通常与较低的晚期瘤发生率有关.
结论:
- 健康的饮食模式与参与CRC查的退伍军人中结肠瘤风险降低有关.
- 需要进一步的研究来探索饮食评估对个性化CRC预防和监测策略的有用性.
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