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Updated: Jan 16, 2026

Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs
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Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs

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解码内质网膜应对冠状细胞的压力 驱动骨关节炎 通过整合单细胞和转录基因剖析来发展骨关节炎

Zhao Zhang1, Debin Cheng1, Jingyi Dang1

  • 1Department of Orthopaedics, Xijing Hospital, The Fourth Military Medical University, Xi'an, China, 710032.

International journal of medical sciences
|October 6, 2025
PubMed
概括

细胞内膜网膜应激 (ERS) 通过激活未折叠的蛋白质反应和软质细胞的亡,驱动骨关节炎 (OA) 的进展. 关键调节剂IGFBP3和S100A4为OA提供了诊断和治疗潜力.

关键词:
细胞内膜网膜应激压力骨关节炎是一种骨关节炎.scRNA分析 scRNA分析

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