眼部慢性淋巴细胞白血病的一种新的呈现
Lauren A Nakhleh1,2, Jamie A Keen2, Elisabeth Sledz1,2
1Loyola University Medical Center, Department of Ophthalmology, 2160 S. First Avenue, Maywood, IL, 60153, United States.
American journal of ophthalmology case reports
|October 6, 2025
概括
这项研究描述了一种罕见的慢性淋巴细胞白血病 (CLL) 病例,该病例影响了患有系统性CLL病史的患者的结膜和. 活检证实了CLL结膜和结膜透,突出了一个独特的眼部表现.
科学领域:
- 眼科医生 眼科 眼科
- 血液学 血液学 血液学
- 在瘤学瘤学.
背景情况:
- 慢性淋巴细胞白血病 (CLL) 是西方国家最常见的白血病.
- 对于CLL的眼部表现相对不常见.
- 结膜和块是CLL参与的罕见地点.
研究的目的:
- 为了记录一种罕见的慢性淋巴细胞白血病 (CLL) 呈现,涉及结膜和.
- 要突出一个独特的系统性CLL的眼部表现.
主要方法:
- 对有系统性CLL病史的患者进行临床检查,并呈现眼部症状.
- 前部段检查显示结膜化解,加厚,以及扩大的.
- 结节细胞和结节细胞活检的组织病理学和免疫组织化学分析 (CD5+ B细胞标记物).
主要成果:
- 患者出现了暗示结膜透的症状.
- 活检证实了小CD5+B细胞淋巴瘤的存在,与结膜和角质的CLL透一致.
- 这代表了CLL在这些眼部结构中的新呈现.
结论:
- 这种病例表明了CLL罕见的眼部表现,涉及结膜和.
- 组织活检和细胞类型测定对于诊断有血性恶性瘤病史的患者的非典型结膜和关节变化至关重要.
- 强调在异常眼部表现时考虑全身性疾病的重要性.
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