对上道泌尿道癌的节约方法:关于当前证据的更新
Ivan Ching Ho Ko1, Chris Ho Ming Wong1, David Ka Wai Leung1
1S.H Ho Urology Centre, Prince of Wales Hospital, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Asian journal of urology
|October 6, 2025
概括
节约性手术 (KSS) 在选择的上道泌尿道癌 (UTUC) 患者中提供了与激进瘤切除术相似的瘤结果. 诊断和治疗方面的进步提高了KSS的适用性,保持了功能.
科学领域:
- 泌尿外科瘤学 泌尿外科瘤学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 手术方面的创新.
背景情况:
- 上道泌尿道癌 (UTUC) 传统上是用激进性瘤切除术治疗的.
- 节手术 (KSS) 正在成为选择性UTUC病例的可行替代方案.
- 诊断和治疗方面的进步正在扩大KSS的作用.
研究的目的:
- 审查节能手术 (KSS) 的最新更新和结果,在患上道泌尿系统癌症 (UTUC) 的患者.
- 与传统治疗相比,评估KSS的瘤疗效和安全性.
- 讨论UTUC管理的诊断工具和治疗剂的进展.
主要方法:
- 在PubMed和Embase数据库中对过去10年的英语语言研究进行了全面的文献搜索.
- 包括使用关键词的研究,如"上泌尿道瘤/癌症/癌瘤"",节性手术或方法"",内镜治疗"",局部灌注"和"尿路标记物".
- 在已识别的文献中评估参考文献的相关性和包含性.
主要成果:
- 对于低风险和选择的高风险UTUC,特别是在单独的病例中,建议使用KSS.
- 在精心挑选的患者中,观察到与KSS (内镜切除,细分泌尿切除,局部灌注) 相比的可比的瘤结局,与激进的脏切除相比.
- 新型诊断工具和风险分层模型有助于在不影响结果的情况下为KSS选择最佳病例.
结论:
- 对UTUC的脏节约方法是泌尿瘤学中一个有前途和不断发展的领域.
- 技术进步,改进的诊断和新型治疗剂正在推动KSS的进步.
- 虽然目前的证据在很大程度上是追溯的,但需要前性试验来回答关键的临床问题.
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