相关实验视频
Updated: Jan 16, 2026

06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
24.2K
阿瓦科班在双阳性血管炎中...为什么不考虑呢? :一个案例报告
Shehab Sayed1, Patricia Torres1, Patricia Purón1
1Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Kidney medicine
|October 6, 2025
概括
在双阳性患者中,快速进展的血小球炎 (RPGN) 的预后不好. 将阿瓦科潘添加到免疫抑制疗法中,改善了患者的功能,突出了其在治疗这种严重病方面的潜力.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 免疫学 免疫学 免疫学
- 内部医学 内部医学
背景情况:
- 抗中性粒细胞质抗体相关的血管炎和抗质底膜疾病可以导致快速进展的质膜炎 (RPGN).
- 在RPGN中双抗体阳性预示着预后不佳,尽管进行了积极的治疗,但往往导致末期病.
研究的目的:
- 报告一个成功管理RPGN的病例,具有双重抗体阳性.
- 评估阿瓦科潘在RPGN复发病例中的疗效.
主要方法:
- 一名72岁的患者接受了活检证明的RPGN和双抗体阳性治疗.
- 最初的治疗包括葡萄糖皮质激素脉冲,利图西马布,环胺和等离子体合成.
- 在疾病复发后添加阿瓦科潘.
主要成果:
- 患者在初始治疗后出现了复发.
- 添加阿瓦科潘导致临床状况和功能逐渐改善.
- 这表明,在耐火病例中,阿瓦科潘可能有益.
结论:
- 积极的免疫抑制策略对于管理抗质底膜疾病至关重要.
- 阿瓦科潘可以作为双抗体阳性RPGN免疫抑制疗法的宝贵补充.
- 早期考虑阿瓦科潘可能会防止进展到晚期慢性病.
相关概念视频
Acute Pancreatitis I: Introduction
1.1K
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.1K
Acute Pancreatitis II: Clinical Manifestations and Management
748
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
748
Acute Pyelonephritis II: Diagnostic Studies and Management
313
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
313
Acute Kidney Injury IV: Diagnostic Studies and Prevention
260
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
260
Pericarditis I: Introduction
333
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
333
Autoimmune Disorders
1.5K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
1.5K

