尿道感染的病因 在新生儿和在克罗地亚的抗菌性
Ana-Meyra Potkonjak1, Ivana Terzić2, Mario Lovrić3
1Department of Obstetrics and Gynecology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Acta clinica Croatica
|October 6, 2025
概括
新生儿尿路感染 (UTI) 很常见,其中大肠杆菌 (Escherichia coli) 和肺炎菌 (Klebsiella pneumoniae) 是主要的原因. 抗生素耐药性是一个越来越令人担忧的问题,影响了克罗地亚的治疗效果.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 新生儿的尿路感染 (UTI) 可能导致严重的并发症,如败血症和脏痕.
- 抗生素耐药性的增加对有效的新生儿尿路感染治疗构成重大威胁.
研究的目的:
- 调查克罗地亚新生儿尿道感染的流行病学.
- 分析常见的抗生素处方模式和致病剂的抗菌耐药性.
主要方法:
- 2005年和2015年新生儿尿路感染病例的回顾性多中心分析.
- 鉴定致病原体并评估它们对抗生素敏感性概况.
主要成果:
- 大肠杆菌 (60.2%) 和肺炎菌 (28.2%) 是主要的病原体.
- 塞夫特里亚克松和安皮西林-胺是常见的经验治疗方法,敏感度为72.7% (2005年) 和75.6% (2015年).
- 观察到大肠杆菌和肺炎菌对常用的抗生素有显著的耐药性.
结论:
- 大肠杆菌仍然是新生儿尿路感染的主要原因,与全球趋势一致.
- 关于细菌耐药性模式的本地数据对于指导新生儿实证抗生素治疗至关重要.
- 需要进一步的前性研究来监测和解决不断发展的抗菌素耐药性.
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