在儿童重症监护病房的儿童中传播呼吸道病毒
Gokhan Ceylan1, Ozlem Sandal1, Ferhat Sari1
11Department of Pediatric Intensive Care Unit, Dr. Behçet Uz Children's Hospital, Izmir, Turkey; 2Department of Pediatric Infectious Diseases Unit, Dr. Behçet Uz Children's Hospital, Izmir, Turkey; 3Department of Infectious Diseases and Clinical Microbiology, Dr. Behçet Uz Children's Hospital, Izmir, Turkey.
Acta clinica Croatica
|October 6, 2025
概括
呼吸道同胞性病毒 (RSV) A/B是儿童下呼吸道感染 (LRTI) 最常见的原因,需要儿童重症监护室 (PICU) 的入院. 潜在的疾病显著影响这些儿童的治疗强度和PICU停留时间.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 急性下呼吸道感染 (LRTI) 是儿童发病率和死亡率的重要原因之一.
- 识别病毒病因对于在重症儿童中管理LRTI至关重要.
研究的目的:
- 确定导致儿科重症监护病房 (PICU) 的儿童中LRTI的呼吸道病毒的分布.
- 分析病毒病原体和潜在疾病对治疗需求和结果的影响.
主要方法:
- 病毒多重聚合酶连锁反应 (PCR) 用于识别入院于PICU的LRTI患者的病毒病原体.
- 收集和分析了患者数据,包括年龄,病毒病因,潜在疾病,治疗方式 (侵入性机械通风,高流氧疗法) 和PICU停留.
主要成果:
- 呼吸道同胞性病毒 (RSV) A/B是PICU入院的LRTI患者中最常见的病毒病原体 (32.8%),主要影响2岁以下的儿童.
- 与接受高流氧疗法 (HFOT) 或标准氧气治疗的患者相比,需要侵入性机械通风 (IMV) 的患者患有更高的潜在疾病 (90%) 和显著更长的PICU停留 (中位数为8天) 的患病率更高.
- 儿科急性呼吸困扰综合征 (PARDS) 在3.3%的患者中发生.
结论:
- 多重PCR对于识别病毒病原体和预测儿科LRTI患者进入PICU的并发症非常有价值.
- 潜在疾病的存在显著影响所需的护理水平和病毒性LRTI的PICU入院时间.
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