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Updated: Jul 15, 2026

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一个六基因线粒体签名预测了脱差甲状腺癌的预后

Chenghui Lu1, Xufu Wang1

  • 1Department of Nuclear Medicine, The Affiliated Hospital of Qingdao University, Qingdao, 266003, People's Republic of China.

International journal of general medicine
|October 6, 2025
PubMed
概括

这项研究确定了六个与线粒体功能障碍相关的基因 (MDRGs),与脱差甲状腺癌 (DDTC) 预后有关. 这些发现为DDTC的向治疗和患者分层提供了洞察力.

关键词:
线粒体功能障碍 线粒体功能障碍预后 预后 预后风险模型的风险模型.甲状腺癌是一种癌症.

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...