评估林戈卡因贴片在第三提取后疼痛管理中的疗效:一个前性,分口研究
P S Tripthi1, Rakshita Kumar1, Padmaraj Hegde1
1Nitte Deemed to Be University, AB Shetty Memorial Institute of Dental Sciences, Department of Oral and Maxillofacial Surgery, Mangalore, India.
Journal of oral biology and craniofacial research
|October 6, 2025
概括
与标准口服止痛药相比,5%的林诺卡因贴片有效地减少了第三提取后的术后疼痛. 这种局部治疗为治疗牙痛提供了一个有希望的替代方案,具有最小的副作用.
科学领域:
- 口腔和牙面部外科手术
- 疼痛管理 疼痛管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 摘取第三骨后的术后疼痛是一个重要的临床问题.
- 目前的治疗方法,如阿片类药物和NSAIDs具有显著的副作用.
- 利格诺卡因贴片提供局部疼痛缓解,系统吸收最小.
研究的目的:
- 评估5%的林戈卡因贴片在第三牙提取后治疗术后疼痛的疗效.
- 为了比较林戈卡因贴片与标准口服止痛药的有效性.
主要方法:
- 一项前性,分口研究,涉及30名接受双边下第三骨提取的患者.
- 利格诺卡因贴片在一侧 (试验) 进行术后施用,在对侧侧 (控制) 施用标准口服止痛药.
- 在手术当天,术后第一天和术后第二天使用视觉模拟尺度 (VAS) 评估疼痛.
主要成果:
- 与对照组 (2.55 ± 0.35,p=0.004) 相比,林可卡因补丁组的VAS平均得分 (1.96 ± 0.72) 显着较低.
- 在手术后的第二天 (p=0.000) 观察到,在林可卡因贴片组中,疼痛减少更大.
- 没有报告任何重大不良反应;13.3%需要第二次贴片,因为无足够的止痛作用.
结论:
- 5%的林戈卡因贴片是第三牙提取后手术后疼痛管理的有效替代品.
- 需要进一步的研究来探索它们在减少阿片类药物消费和在其他口腔手术中的适用性方面的作用.
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