在接受脊柱骨折手术的患者中,为外科手术期间下肢DVT的临床风险预测模型
ShuYuan Zhuang1,2, Jing Wang2, Peng Du3
1School of Nursing, Inner Mongolia Medical University, Hohhot, China.
Frontiers in surgery
|October 6, 2025
概括
本研究确定了脊椎骨折手术患者深静脉血栓形成 (DVT) 的关键风险因素,开发了一个预测模型,以帮助临床预防策略和改善患者的治疗结果.
科学领域:
- 整形外科手术 整形外科手术
- 血管医学 血管医学
- 临床流行病学 临床流行病学
背景情况:
- 深静脉血栓 (DVT) 是脊柱骨折手术后的一个重大风险.
- 有效的术后风险分层对于预防这种脆弱患者群体的DVT至关重要.
研究的目的:
- 在接受脊柱骨折手术的患者中开发和验证外科手术期间下肢DVT的预测模型.
- 在这个队列中确定与外科手术期间DVT相关的独立风险因素.
主要方法:
- 对249名脊柱骨折手术患者的临床数据进行了回顾性分析.
- 后勤回归分析以确定独立的风险因素并建立预测模型.
- 使用Hosmer-Lemeshow适合性测试和ROC曲线分析用于预测性能的模型验证.
主要成果:
- 确定了独立的危险因素:外科手术前输血,高C反应蛋白,D-二次数>500μg/L,高血压,年龄≥60岁,以及长时间的卧床休息.
- 开发的模型表现出良好的适应性 (霍斯默-莱梅Show P=0.807) 和强大的预测性能 (AUC 0.75-0.81).
结论:
- 已识别的风险因素是脊椎骨折患者外科手术期DVT的关键预测因素.
- 提出的预测模型为早期风险分层和指导预防性干预提供了强大的临床实用性.
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