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穿皮穿孔使用一种新的对比增强超声指导技术:第一个猪模型体验
Donglai Shen1, Shoupeng Li2, Hairui Chen1,3
1Department of Urology, the Third Medical Center, Chinese PLA General Hospital, Beijing, China.
European urology open science
|October 6, 2025
概括
在一项临床前研究中,一项新的双对比增强超声波 (D-CEUS) 技术改善了收集系统穿孔成功率,并在皮肤穿神经切除术期间减少了血管损伤.
科学领域:
- 医疗成像医学成像
- 手术技术 手术技术
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 穿皮瘤切除术 (PCNL) 涉及穿孔收藏系统.
- 对于PCNL的成功和安全而言,非扩展收集系统的准确定位至关重要.
- 传统的超声波指导在刺穿期间可视化关键结构方面存在局限性.
研究的目的:
- 引入和评估一种新的双对比增强超声波 (D-CEUS) 技术.
- 评估D-CEUS的可行性和安全性,用于在临床前环境中进行脏收集系统穿刺.
- 为了比较D-CEUS指导与PCNL的常规超声波.
主要方法:
- 开发了一种D-CEUS技术,用于指导穿孔.
- 在六只猪身上进行了皮穿刺,D-CEUS用于左,常规超声波用于右.
- 测量结果包括首次尝试成功率,穿刺时间和血管损伤发生率.
主要成果:
- 与传统超声波相比,D-CEUS显示出明显更高的第一次尝试成功率 (94.4%vs. 61.1%).
- D-CEUS导致血管损伤的发生率较低 (0%vs.27.8%) 和穿孔时间较短 (26s vs. 45s).
- 正确的穿孔率也更高的D-CEUS (100%对66.7%).
结论:
- D-CEUS提供了血管解剖和针轨迹的实时可视化,提高了穿刺精度.
- 这种技术有潜力提高皮肤穿神经切除术的安全性和效率.
- 临床验证是必要的,以确认这些临床前发现.
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