对于双端读出TOF-DOI PET检测器的时间步行和时间转移校正方法
Haibo Wang1, Jiahao Xie1, Jinyi Qi1
1Department of Biomedical Engineering, University of California at Davis, Davis, CA 95616 USA.
IEEE transactions on radiation and plasma medical sciences
|October 6, 2025
概括
这项研究引入了一种新的校正方法,用于双端读出定子发射断层扫描 (PET) 探测器中的时间步行和时间转移. 该技术显著提高了巧合时间分辨率,提高了PET成像性能.
科学领域:
- 医疗成像医学成像
- 核物理 核物理 核物理
- 仪器化 仪器化 仪器化
背景情况:
- 定子发射断层扫描 (PET) 探测器面临时间不准确性,如时间行走和时间转移.
- 这些问题源于尖端的分辨器和厚晶体中的相互作用深度 (DOI) 效应.
- 精确的定时对于高分辨率PET成像至关重要.
研究的目的:
- 开发和评估双端读出PET检测器中时间行走和时间转移的综合校正方法.
- 为了提高PET系统的巧合时间分辨率 (CTR).
- 提高PET扫描仪的整体性能和图像质量.
主要方法:
- 提出了一种新的结合时间步行和时间转移校正算法.
- 双端读出PET探测器是使用光倍增器 (SiPM) 阵列和LYSO晶体构建的.
- 事件能量与检测到的时间差异之间的关系被用于校正.
- 应用了一个能量窗口 (400-650 keV) 来选择有效的事件.
主要成果:
- 提出的方法有效地纠正了时间行走和时间转移.
- 巧合时间分辨率从260.7 ± 1.0 psi提高到229.4 ± 1.0 ps.
- 结果表明,PET探测器的计时精度显著提高.
结论:
- 开发的校正方法对于双端读出PET检测器是有效的.
- 这种技术提供了一种可行的解决方案,以提高PET成像中的定时分辨率.
- 这些发现有助于推进高性能PET扫描仪技术的发展.
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