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Updated: Jan 15, 2026

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
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来自前列腺瘤的细胞外囊泡以mTOR/RAB1A依赖的方式重塑转移前的骨环境

Tingting Lv1, Yawen Guo1, Yuehua Zhang1

  • 1Department of Immuno-Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

Frontiers in immunology
|October 6, 2025
PubMed
概括

这项研究揭示了mTOR/RAB1A信号如何控制前列腺癌 (PCa) 骨转移中的细胞外囊 (EV) 分泌. 抑制EV分泌提供了一种治疗策略,通过逆转免疫抑制来抵抗骨转移.

关键词:
乙型淋巴细胞B型淋巴细胞拉伯1A 拉伯1A 是一个字.细胞外囊泡中的细胞外囊泡.在前转移前的利基.前列腺癌是前列腺癌.

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