在中国湖南艾滋病毒/艾滋病感染者中,不可检测=不可传播的感知及其与性风险行为及其潜在的身体和心理益处的关联
Yuqiong Duan1, Yixuan Li1, Ziqi Qin1
1Xiangya School of Nursing, Central South University, Changsha, Hunan, People's Republic of China.
Patient preference and adherence
|October 6, 2025
概括
无法检测 = 无法传播 (U=U) 意思是如果病毒载量无法检测,艾滋病毒无法通过性传播. 许多艾滋病毒感染者 (PLWH) 缺乏对U=U的充分理解和接受,影响健康结果和艾滋病毒预防策略.
科学领域:
- 艾滋病毒/艾滋病研究研究
- 公共卫生 公共卫生
- 社会科学 社会科学 社会科学
背景情况:
- 不可检测=不可传播 (U=U) 是科学共识,即携带艾滋病毒的人 (PLWH) 保持不可检测的病毒载荷不能通过性传播传播艾滋病毒.
- 了解U=U对于PLWH从治疗和预防策略中获益至关重要.
- 对U=U的有限知识和接受可能会影响性行为和健康结果.
研究的目的:
- 探索PLWH对U=U的看法,包括知识,态度和接受.
- 检查U=U感知与性行为之间的关系.
- 调查U=U感知与身体/心理益处之间的关联,包括ART坚持和病毒载量.
主要方法:
- 一项涉及730名来自门诊的18岁以上PLWH的横截面研究.
- 通过匿名,纸质问卷收集的关于U=U感知,性风险行为和健康益处的数据.
- 统计分析包括多重逻辑回归,以及使用Poisson和Gamma回归器的通用线性模型 (GLM).
主要成果:
- 虽然超过一半的参与者听说过U=U,但只有13.6%的人对U=U有全面的了解,而19.9%的人接受它作为预防策略.
- 较低的U=U知识与可检测或无法检测的病毒载量和无法检测的CD4+细胞数量有关.
- 较高的U=U接受与增加的无保护性行为相关;负面态度与无法获得的病毒数据有关.
结论:
- 由于不完全理解和接受,PLWH尚未完全意识到U=U的好处.
- 需要有针对性的策略来传播准确的U=U信息,并传达其个人和社会利益.
- 进一步的研究应侧重于提高U=U意识和接受,以便更好地管理和预防艾滋病毒.
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