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在过敏性鼻炎患者中鉴定皮下免疫疗法不服药的原因:一个横截面研究

Cheng-Zhi Huang¹, Zhi-Yuan Tang¹

¹Department of Otorhinolaryngology, Shenzhen University General Hospital, Shenzhen, Guangdong, People's Republic of China.

Patient preference and adherence

|October 6, 2025

概括

转移和感知到缺乏疗效是停止皮下免疫疗法 (SCIT) 在过敏性鼻炎 (AR) 患者的主要原因. 解决患者的期望和后勤问题可以改善治疗坚持.

科学领域:

过敏和免疫学过敏和免疫学
耳鼻喉科耳鼻喉科耳鼻喉科
药理学药理学是指药理学的学科.

背景情况:

过敏性鼻炎 (AR) 显著影响生活质量.
皮下免疫疗法 (SCIT) 是对AR的有效治疗方法,但坚持可能具有挑战性.
了解停止SCIT治疗的原因对于改善患者的治疗结果至关重要.

研究的目的:

确定AR患者中SCIT中止的主要原因.
为旨在提高治疗坚持和SCIT的长期成功的战略提供信息.

主要方法:

一项回顾性横截面研究包括794名AR患者,他们启动了标准化的SCIT.
通过结构化电话跟踪收集了关于SCIT停药,原因和患者人口统计数据.
通过视觉模拟尺度 (VAS) 减少和患者报告的改善来评估有效性.

主要成果:

7.30%的患者停止了SCIT,搬迁是最常见的原因 (53.45%).
感知缺乏疗效 (17.24%),时间有限 (8.62%) 和怀孕 (6.90%) 是其他重要因素.
由于搬迁,女性更有可能停止使用,而男性更经常引用不满意的疗效.

结论:

停用SCIT主要受到搬迁,治疗期望和后勤挑战的影响.
在停药原因中观察到特定于性别的模式.
量身定制的治疗前咨询和生活方式/生殖计划的积极管理可以改善SCIT的坚持.

关键词:

长期治疗的挑战.患者的随访情况城市生活方式的因素

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