不良的童年经历,抑郁症和性别主观认知衰退:一个温和的调解分析
Monique J Brown1,2,3,4,5, Darlingtina K Esiaka6,7, Jaya Viswanathan8
1Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
概括
儿童不良经历 (ACE) 与认知能力下降有关,抑郁症发挥着关键的调解作用. 针对ACE的干预措施可以改善男性和女性的认知功能.
科学领域:
- 心理学 心理学 心理学
- 公共卫生 公共卫生
- 神经科学是一个神经科学.
背景情况:
- 童年不良经历 (ACE) 与长期的健康后果有关.
- 主观认知衰退 (SCD) 是一个日益严重的公共卫生问题.
- 抑郁症在ACE和SCD之间扮演的调解角色需要进一步调查.
研究的目的:
- 检查抑郁症对ACE和SCD之间的关系的调解效应.
- 评估性别对这种关联的温和影响.
主要方法:
- 利用了2023年行为风险因素监测研究 (BRFSS) 调查的数据 (N = 38,600).
- 采用原始和调整路径分析来调查调解.
- 在调整后的分析中对社会人口统计学混因素进行了控制.
主要成果:
- ACEs显示出与抑郁症有显著的积极关联 (B = 0.129,p < 0.001).
- 抑郁症与SCD有显著的相关性 (B = 0.224,p < 0.001).
- 抑郁症在男性和女性总人口中显著调解了ACE和SCD之间的关联.
结论:
- 抑郁症在不良童年经历和主观认知衰退之间起着重要的调解作用.
- 专注于ACE的干预计划可能为减少抑郁和增强认知功能提供了一条途径.
- 调查结果在两性之间一致,表明干预措施的广泛适用性.
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