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内視鏡腹腔皮羅羅美托米與腹視鏡胃電動刺激器為胃衰:一個傾向得分匹配的多中心試驗

Seung Hyeon Shim¹, Jesse Cheng¹, Haitong Yu¹

¹From the, Case Western Reserve University School of Medicine, Cleveland, OH (Shim, Cheng, Yu, Lee, Katta, El-Hayek).

Journal of the American College of Surgeons

|October 6, 2025

概括

胃口内视镜肌切除术 (G-POEM) 比胃电刺激 (GES) 治疗胃衰竭更少侵入性,更有效. G-POEM提供更好的症状控制和更低的复发率,使其成为首选的初始治疗选择.

科学领域:

胃肠病学胃肠病学
最少侵入性的手术
医疗器械技术医疗器械技术

背景情况:

耐药性胃衰竭显著影响患者的福祉.
目前的内镜和手术干预缺乏明确的治疗指南.
对比口腔胆道肌瘤术 (POP/G-POEM) 和胃电刺激器 (GES) 对于治疗选择至关重要.

研究的目的:

为了比较POP/G-POEM与GES在治疗胃衰竭的安全性和有效性.
评估术后结果,症状改善和复发率.
确定耐火性胃衰竭的最佳第一线治疗方法.

主要方法:

在两个大批量中心接受POP/G-POEM或GES的226名患者的回顾性审查.
根据年龄,性别和胃衰竭原因进行倾向分数匹配 (1:1比).
对术后结果,症状评分 (胃衰竭主要症状指数),BMI变化,复发率和重新干预率的分析.

主要成果:

与GES相比,POP/G-POEM显著减少了手术时间,血液损失和住院时间.
这两种手术的立即并发症和一年的再干预率都相似.
POP/G-POEM显示症状复发率较低 (41.6%) 与GES (78.8%) 相比.

结论:

POP/G-POEM与较低的发病率和比GES更高的有效性有关.
应考虑POP/G-POEM作为耐药性胃衰竭的首选初始治疗方法.
内镜肌肉切除术为基于设备的治疗提供了一个有前途的替代方案,用于胃衰竭管理.

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