在名义体积上进行例行后扩张,以优化气球扩展的扩张:双研究
Ali Husain1,2, Julius Jelisejevas1,3, Kevin Millar1
1Centre for Heart Valve Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
概括
在气球可扩展跨导管大动脉植入 (TAVI) 之后,在具有有利解剖的患者中,常规的双击改善了门扩张,而没有安全问题. 需要进一步的研究来评估对门功能的长期影响.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 在TAVI后,气球可扩展的透气管心脏门 (THV) 的不完全扩张可能会发生.
- 临时后扩张是一种常见但未经评估的THV不扩张的治疗方法.
- 使用原始气球 (双击) 进行例行后扩张可以安全地改善THV扩张.
研究的目的:
- 评估气球可扩展TAVI后的例行双击的安全性和有效性.
- 为了评估双点击对接受SAPIEN 3 Ultra门的患者THV扩张的影响.
主要方法:
- 预期包括使用SAPIEN 3 Ultra (S3U) 门进行TAVI的患者.
- 排除患有严重环状或亚环状化的患者.
- 光镜分析测量THV截面面积在双击前后;记录了30天的临床结果.
主要成果:
- 在102名患者中进行了例行双击,所有患者最初都显示出一些不扩张.
- 在各种S3U门尺寸中观察到THV扩张的显著增加 (例如,23毫米的9.9%,p<0.001).
- 在30天内没有发生中风或心血管死亡.
结论:
- 常规的双点击有效地改善了THV扩张在接受TAVI的有利解剖的患者.
- 该战略表明没有立即的安全问题.
- 对THV功能,血液动力学和耐久性的长期影响需要进一步研究.
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