Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

IP3/DAG Signaling Pathway01:11

IP3/DAG Signaling Pathway

14.3K
Membrane lipids such as phosphatidylinositol (PI) are precursors for several membrane-bound and soluble second messengers. Specific kinases phosphorylate PI and produce phosphorylated inositol phospholipids. One such inositol phospholipids are the  phosphatidylinositol-4,5 bisphosphate [PI(4,5)P2], present in the inner half of the lipid bilayer. Upon ligand binding, GPCR stimulates Gq proteins to turn on phospholipase Cꞵ. Activated phospholipase Cꞵ cleaves PI(4,5)P2 and...
14.3K
Protein Networks02:26

Protein Networks

4.5K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.5K
Protein Networks02:26

Protein Networks

2.8K
2.8K
Nursing Clinical Information System01:27

Nursing Clinical Information System

1.2K
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Intranodal Hemangioma as a Differential Diagnosis of Melanoma Metastasis: A Case Report of a Rare Entity.

Acta dermatovenerologica Croatica : ADC·2026
Same author

Predictive Value of Preoperative Positron Emission Tomography/Computed Tomography (PET/CT) in Staging of Patients with High-Risk Melanoma.

Acta dermatovenerologica Croatica : ADC·2026
Same author

3D radiomics profiling of thyroid tumors using micro-CT.

Scientific reports·2026
Same author

UveAI: clinic-ready scoring of retinal inflammation in uveitis on widefield fluorescein angiography using AI.

Scientific reports·2026
Same author

European Dermatologists' Perception and Awareness of Teledermatology Use: Results From an International Survey Promoted by the EADV Teledermatology Task Force.

International journal of dermatology·2026
Same author

Cytokine Profiling in Cutaneous Melanoma: The Emerging Role of Interleukins in Prognostic Stratification with an Up-to-Date Overview of Published Data.

Journal of personalized medicine·2026

相关实验视频

Updated: Jan 15, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

16.0K

诺戴 (NOODAI):一个面向网络的多业务数据分析和集成管道的网络服务器.

Tiberiu Totu1,2,3, Rafael Riudavets Puig1,2, Lukas Jonathan Häuser1,2,3

  • 1Nanomaterials in Health Laboratory, Swiss Federal Laboratories for Materials Science and Technology (Empa), 9014 St. Gallen, Switzerland.

Bioinformatics (Oxford, England)
|October 6, 2025
PubMed
概括

本研究介绍了NOODAI,这是一个用于整合性奥米克分析的软件平台. 它从omics数据构建联合交互网络,以识别关键的生物特征和与疾病相关的模块,增强表型的理解.

更多相关视频

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

3.9K
A Web-Based Workflow for Selecting Gene- and Tissue-Specific Enhancers
08:12

A Web-Based Workflow for Selecting Gene- and Tissue-Specific Enhancers

Published on: July 18, 2025

609

相关实验视频

Last Updated: Jan 15, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

16.0K
An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

3.9K
A Web-Based Workflow for Selecting Gene- and Tissue-Specific Enhancers
08:12

A Web-Based Workflow for Selecting Gene- and Tissue-Specific Enhancers

Published on: July 18, 2025

609

科学领域:

  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学
  • 系统生物学 系统生物学

背景情况:

  • 在确定生物表型和疾病的分子特征方面,Omics 分析至关重要.
  • 分析个人奥米克数据提供了特定的分子洞察力.
  • 对多学科数据的联合评估可以更深入地了解生物系统的功能.

研究的目的:

  • 从omics数据构建和分析联合交互网络的新方法.
  • 开发NOODAI软件平台,用于用户友好的整合性电脑分析.
  • 利用网络分析来识别关键的生物特征和功能连接的模块.

主要方法:

  • 从每个奥米克特征的代表性特征构建联合交互网络.
  • 利用生物实体之间自信相互作用的现有知识.
  • 使用MONET网络分解工具来识别功能连接的模块.
  • 开发了NOODAI软件平台,具有用户友好的界面.

主要成果:

  • 在联合网络中识别连接多个表型特征实体的中心元素.
  • 使用MONET.突出显示功能连接的网络模块.
  • 诺代提供原始输出表,摘要图表和书面报告.
  • 该平台可以广泛用于整合性奥米克分析.

结论:

  • 欧米克特征分析对于对表型定义特征的公正识别是有价值的.
  • 联合奥米克分析为生物系统提供了更深入的见解.
  • 诺代软件平台有助于整合性奥米克分析和疾病相关模块的识别.
  • NOODAI对于分析临床多omics数据集非常有价值.