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Updated: Jan 15, 2026

Estimation of Telomeric Repeat-containing RNA from DNA/RNA Hybrid Complexes
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RNA G-四重复RIBOTAC介导的 lncRNA TERRA 的目标降解

Elias Khaskia1, Dipak Dahatonde1, Raphael I Benhamou1

  • 1The Institute for Drug Research of the School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 9112002, Israel.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|October 6, 2025
PubMed
概括

新的RIBOTAC技术针对TERRA (端粒重复含有RNA) 来降解在癌细胞中. 这种方法表明,通过准RNA调节,开发新型癌症疗法具有前途.

关键词:
这是一个G-四重复式.里博塔克 (RIBOTAC) 是一个替代性延长端粒的方法在ncRNA中,我们可以小分子的小分子.有针对性的降解降解目标.

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