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Updated: May 6, 2026

An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry
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无抗体直线双保留纳米-WCX-μSPE-MS/MS用于定量临床血清中的完整甲状腺激素和对抗性碎片

Anping Wang1, Jinlan Yang1, Siqi Zhao1

  • 1Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, China.

Analytical chemistry
|October 6, 2025
PubMed
概括

一种新的质谱法准确地测量了副甲状腺激素 (PTH) 和其抗体在患者血清中. 这种无抗体的方法提高了慢性病 (CKD) 患者骨病的诊断准确度.

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相关概念视频

Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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