视力障碍和全因和因特定死亡率的风险:来自两个前性队列研究的结果
Xing-Xuan Dong1, Jia-Yan Kai1, Dan-Lin Li1
1From the School of Public Health (X-X.D., J-Y.K., D-L.L., C.K., C-W.P.), Suzhou Medical College of Soochow University, Suzhou, China.
American journal of ophthalmology
|October 6, 2025
概括
视力障碍 (VI) 与所有死因,特别是心脏病的死亡风险更高有关. 早期发现和管理VI,以及心血管保健,对于公共卫生至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 视力障碍 (VI) 影响了相当一部分成年人群.
- 了解与VI相关的死亡风险对于公共卫生倡议至关重要.
研究的目的:
- 为了确定视力障碍 (VI) 和全因死亡率之间的关联.
- 调查VI和特定原因死亡率,特别是心脏病之间的联系.
主要方法:
- 基于人口的队列研究,利用美国国家健康和营养检查调查 (NHANES) 和英国生物库的数据.
- 包括12,510名40岁及以上的美国成年人和95,477名英国成年人.
- 考克斯的比例危险和竞争风险模型被用来分析死亡率数据.
主要成果:
- 经过调整后的分析显示,VI患者的全因死亡风险比率显著上升 (美国NHANES:HR=1.63;英国生物银行:HR=1.25).
- 在美国NHANES队列中发现VI和心脏病特异性死亡率之间存在显著的关联 (HR=1.76),通过竞争性风险分析 (HR=1.34) 得到证实.
结论:
- 视力障碍独立地与全因和心脏病特异性死亡率的风险增加有关.
- 将VI的早期检测和管理与心血管风险预防策略相结合,对公共卫生具有重要意义.
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