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Updated: Jan 15, 2026

Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
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Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice

Published on: August 12, 2014

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由阿克罗林诱导的PKM2修饰驱动NETosis和质瘤进展

Hsiang-Tsui Wang1, Zhen-Jie Tong2, Ya-Rou Lin2

  • 1Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan; Institute of Food Safety and Health Risk Assessment, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan; Doctor Degree Program in Toxicology, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.

Free radical biology & medicine
|October 6, 2025
PubMed
概括

一种与脑瘤相关的分子阿克罗莱因,驱动了在质母细胞瘤中中性粒细胞外细胞陷 (NET) 的形成. 抑制这种称为NETosis的过程,可能为侵袭性脑癌提供一种新的治疗策略.

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