一个监测干预忠实的框架:NOURISH试验
Jennifer Ventrelle1, Beth Lukaszewicz2, Megan Claysen2
1Department of Clinical Nutrition, Rush University Medical Center, Chicago, IL 60612, United States of America; Department of Family and Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, United States of America.
在NOURISH试验中评估治疗忠实度可以确保像MIND饮食这样的饮食干预措施得到一致的交付. 这有助于确认饮食是否有效减缓中风幸存者的认知衰退.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 营养显著影响慢性疾病的结果,需要对治疗忠实性的评估.
- NOURISH试验调查了地中海-DASH干预神经退行性延迟 (MIND) 饮食对中风幸存者的认知衰退的影响.
- 确保一致的干预交付对于将结果归因于饮食干预至关重要.
研究的目的:
- 在NOURISH III期饮食干预试验中评估治疗忠实度.
- 确保一致的交付和参与者参与MIND饮食干预.
- 根据参与者的需求和在中风恢复期间的坚持来完善干预.
主要方法:
- 开发了基于五个关键组件的治疗忠实性的模板和措施.
- 评估干预设计,协议,培训,交付,接收和颁布.
- 使用定期评估来监测干预的一致性和参与者的理解.
主要成果:
- 定期评估证实了根据协议的一致的干预交付.
- 研究参与者的理解和愿意采用MIND饮食.
- 该干预措施得到了改进,以更好地满足不同类型的中风幸存者的需求.
结论:
- 保持干预的忠实性,同时允许适应性是中风恢复公共卫生计划的关键.
- 对于可靠的干预结果,对治疗忠实性的一致评估至关重要.
- NOURISH试验为评估临床环境中的饮食干预提供了一个模型.
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