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Updated: Jan 15, 2026

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间歇性前庭神经瘤的临床流行病学
Martin Reznitsky1, Sven-Eric Stangerup1, Per Cayé-Thomasen2
1Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Handbook of clinical neurology
|October 6, 2025
概括
由于更好的诊断和人口老龄化,前庭神经瘤 (VS) 的发病率有所增加,而不是病例的真正增加. 早期检测会导致较小的瘤和更好的听力结果.
科学领域:
- 神经瘤学神经瘤学
- 流行病学 流行病学
- 神经外科 神经外科
背景情况:
- 静脉神经瘤 (VS) 流行病学显示出流行和发病率的不断变化的趋势.
- 了解这些趋势对于诊断和治疗计划至关重要.
研究的目的:
- 分析丹麦1976-2016年间散发性前庭神经瘤 (VS) 的临床流行病学.
- 将这些发现与VS的全球数据进行比较.
主要方法:
- 丹麦所有零星VS患者的前性,未经选择的国家队列研究.
- 从1976年到2016年收集数据,包括瘤大小,诊断时的年龄和听力结果.
主要成果:
- 截至2016年,丹麦的VS患病率为0.058%.
- 每年诊断的VS病例从14个增加到193个;诊断瘤大小从26mm减少到7mm.
- 诊断时的平均年龄从49岁增加到61岁;听力结果显著改善 (35%到70%的言语歧视).
结论:
- 越来越多的VS发病率归因于增强的诊断能力和人口老龄化.
- 诊断意识的提高导致较小瘤的早期检测和更好的患者预后.
- 尽管发病率上升,但无症状VS的患病率可能稳定.
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