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Updated: Jan 15, 2026

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
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Published on: December 19, 2019

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乙化依赖USP7-TRIM25轴驱动非小细胞肺癌的瘤性进展

Jian Yang1,2, Zhike Chen1,2, Wenxuan Hu1,2

  • 1Department of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Suzhou, Jiangsu Province, China.

Cell death & disease
|October 6, 2025
PubMed
概括

含有25 (TRIM25) 的三方基因在非小细胞肺癌 (NSCLC) 中高度表达,促进瘤生长和扩散. 由CBP对lysine 392的乙化,由SIRT7抵消,调节TRIM25的稳定性,并提供一种潜在的抗癌策略.

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