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Updated: Jan 15, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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NAA60促进了LRRC8A和LRRC8D介导的制药的吸收

Carmen Alexandra Widmer1,2, Anna Moyseos1,2, Ismar Klebic1,3

  • 1Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Communications biology
|October 6, 2025
PubMed
概括

NAA60,一个N端乙转移酶,乙化LRRC8A/D子单元对于基化疗吸收至关重要. 这种乙化对药物疗效至关重要,而它缺失导致BRCA1突变癌症的耐药性.

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