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Updated: Jan 15, 2026

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多样样单细胞RNA-seq数据的差异检测工作流程

Jeroen Gilis1,2, Laura Perin3, Milan Malfait1

  • 1Department of Mathematics, Computer science and Statistics, Ghent University, Krijgslaan 281, Ghent, 9000, Belgium.

BMC genomics
|October 6, 2025
PubMed
概括

本研究介绍了单细胞RNA测序 (scRNA-seq) 的差异检测 (DD) 工作流程,以分析基因表达分数. 对DE和DD的联合分析为基因发现和功能解释提供了互补的见解.

关键词:
基准测试 (benchmarking) 是一种比较的方法.伪布鲁克聚合 伪布鲁克聚合scRNAseq数据分析的数据分析.在场/不在场.

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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