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Updated: Aug 2, 2026

Enhanced Sample Multiplexing of Tissues Using Combined Precursor Isotopic Labeling and Isobaric Tagging cPILOT
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为高通量蛋白质组量化提供13个复合的DeAla异构体试剂

Peng-Kai Liu1, Ting-Jia Gu2, Shuling Xu2

  • 1Biophysics Graduate Program, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.

Analytical chemistry
|October 7, 2025
PubMed
概括

我们开发了一种新的,价格实惠的等离子标记试剂DeAla用于质谱. 这种具有成本效益的工具可以改善片段分裂和蛋白质识别,使大规模的定量蛋白质组学更容易获得.

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Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order to...