静脉注射lignocaine输注对手术内需要的desflurane的影响:一个随机对照试验
Syarifah Noor Nazihah Sayed Masri1, Wilson Anak Matthew Rona2, Nurul Alina Muhamad Suhaini1
1Department of Anaesthesiology and Intensive Care, Faculty of Medicine & Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur, Malaysia.
静脉注射的林诺卡因输液显著降低了需要的潮结束时的德斯弗隆度和腹腔镜手术期间的成本. 这种方法保持稳定的双光谱指数尺度值,没有不良的血液动力学影响,证明可用于减少麻醉剂需求.
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 在外科手术期间,静脉注射林戈卡因输液显示出最小的膜度节约效应.
- 这项研究研究了IV线性林古卡因对手术内末尾潮 (Et-Des) 度的影响,以维持双光谱指数尺度 (BIS) 在40-60之间.
研究的目的:
- 为了评估静脉注射林戈卡因输注对所需的手术后期潮结束时的德斯兰度的影响.
- 评估腹腔镜手术期间对麻醉成本和血液动力学稳定性的影响.
主要方法:
- 进行腹腔镜手术的48名患者被随机分为两组.
- 组A接受了IV胆固醇林戈卡因,随后输注;组B接受了正常的盐水.
- 在整个过程中,对BIS,心率,平均动脉压和Et-Des度进行了监测.
主要成果:
- 与B组相比,A组的Et-Des度明显较低 (4.3%±0.45%) (5.3%±0.56%).与B组相比,A组的Et-Des度明显较低 (4.3%±0.45%).
- 在林戈卡因组中,德斯弗兰的成本显著降低 (RM 35.79 ± 7.43 与RM 46.37 ± 9.75 相比).
- 两组之间没有观察到心率或平均动脉压的显著差异.
结论:
- 静脉注射林戈卡因输液有效降低了Et-Des度,数量和维护BIS 40-60的成本.
- 这种对麻醉的辅助是可行的,没有显著的血液动力学变化或副作用.
- 在腹腔镜腹腔外科手术中,注射lignocaine是一种可行的选择,可以减少对麻醉剂的需求.
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