身体形状指数与骨关节炎之间的关联:使用NHANES数据 (1999-2020) 的横截面研究
Zhen Ai1, Jing-Xuan Cui1, Yang Yang1
1Heilongjiang University of Chinese Medicine, Heilongjiang, China.
Medicine
|October 7, 2025
概括
较高的A体形指数 (ABSI) 与骨关节炎 (OA) 风险增加有关,特别是在男性和年轻人中. 这种腹部肥胖度测量突出了针对OA预防策略的特定人群.
科学领域:
- 整形外科 整形外科 整形外科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 骨关节炎 (OA) 是一种常见的退行性关节疾病,具有复杂的风险因素.
- 身体形状指数 (ABSI) 和OA之间的关联,特别是性别和年龄特定的差异,尚未得到充分理解.
- ABSI结合腰围,BMI和身高来评估身体形状和腹部肥胖.
研究的目的:
- 调查ABSI和OA患病率之间的关系.
- 检查ABSI-OA协会中的性别特异性和年龄相关变化.
- 为了识别潜在的风险分层,使用ABSI对OA.
主要方法:
- 从国家健康和营养检查调查 (NHANES) 数据库 (1999-2020) 中对39,095名美国成年人的分析.
- 使用公式计算ABSI:WC (m) / [BMI (kg/m2) 2/3 × 身高 (m) 1 / 2].
- 用权重多变量调整后勤回归模型来评估ABSI和OA之间的关联,包括子组分析.
主要成果:
- 在ABSI和OA之间发现了显著的正相关性 (OR:每0.01增加1.13).
- 与最低四分位数相比,最高的ABSI四分位数显示OA风险增加了24%.
- 这种关联在男性 (OR: 1.32) 和年轻至中年成人 (OR: 1.17) 中较强,但在女性或老年人中并不显著.
结论:
- 较高的ABSI,表明腹部肥胖,是OA风险的独立预测指标.
- 根据性别和年龄组,ABSI-OA协会表现出显著的差异.
- ABSI可以作为一种有价值的工具来识别患有OA风险较高的个体,特别是在特定的人口亚群中,指导有针对性的干预措施.
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