通过手动地图导航的目标下一代测序来诊断的外围肺结核:一个病例报告
Peng Zou1,2, Yapei Cui1,2, Ning Zhang3
1Department of Respiratory and Critical Care Medicine, The Eighth Clinical Medical School of Guangzhou University of Chinese Medicine, Foshan, China.
Medicine
|October 7, 2025
概括
诊断外围肺结核可能很困难. 手动绘图导航与目标下一代测序 (tNGS) 结合,有助于诊断肺病变,即使没有先进的支气管镜检查.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 医疗成像医学成像
背景情况:
- 周围肺结核 presents诊断上的挑战,经常模仿肺癌.
- 早期和准确的诊断对于有效的治疗至关重要.
研究的目的:
- 报告一个使用手动绘图导航和目标下一代测序 (tNGS) 诊断的外围肺结核病例.
- 突出这些技术在具有挑战性的外围肺损伤病例中的实用性.
主要方法:
- 一名29岁的男性在CT扫描上呈现出一个未确定的肺结节.
- 进行了支气管透镜活检,刷牙和支气管膜洗,以手动地图导航为指导.
- 针对性下一代测序 (tNGS) 用于病因诊断.
主要成果:
- 病理学发现了淋巴细胞透和间歇性纤维组织增生.
- tNGS在支气管支气管洗液中检测到Mycobacterium结核综合体.
- 患者接受了抗结核治疗,导致随访CT时结节减少.
结论:
- 手动地图导航和tNGS是诊断外围肺病变的宝贵工具,特别是在资源有限的环境中.
- 这种综合方法可以提高对肺结核等具有挑战性的肺病理的诊断产量.
关键词:
支气管镜检查 (bronchoscopy) 是一种用来检查支气管.案例报告案例报告手动绘图导航导航的使用周围肺部病变的病变有针对性的下一代测序.结核病 (tuberculoma) 是一种肺结核病.更多相关视频
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