不间断和间断的坐着对长期COVID的成年人血管功能的影响
Nick Hudson1, Scott Hannah1, Margaret Husted2
1School of Sport, Health and Community, University of Winchester, Winchester, UK.
Physiological reports
|October 7, 2025
概括
与对照人群相比,长期COVID (LC) 患者对长时间坐着的血压或动脉硬反应没有改变. 在任何一组中,通过轻度体力活动 (LPA) 打断坐姿并没有减轻这些影响.
科学领域:
- 心血管生理学心血管生理学
- 运动科学 运动科学
- 长时间的COVID研究
背景情况:
- 长时间坐着会急剧增加血压 (BP) 和动脉硬 (AS).
- 轻度体力活动 (LPA) 可以减轻这些不良影响.
- 长期COVID (LC) 可能会导致血管并发症,但其对坐着引起的血管变化的影响尚不清楚.
研究的目的:
- 为了确定患有LC的个体是否表现出改变了不间断坐着的BP/AS反应.
- 评估LC是否影响缓解BP/AS应答,以LPA.中断的坐着.
- 为了比较LC患者与健康对照者的血管反应.
主要方法:
- 30名LC和15名对照组的参与者接受了2小时的不间断的坐着和与LPA中断的坐着.
- 中心和外周血压,以及带-大腿脉冲波速率 (cfPWV) 在干预前和后被测量.
- 线性混合效应模型被用于分析数据.
主要成果:
- 在两组中,不间断地坐着显著增加了中心心和腹血压.
- 在任何一组中坐下后,没有观察到动脉硬度 (cfPWV) 的显著变化.
- 打断与LPA坐在一起并没有显著改变BP或AS对坐在一起的反应,无论LC状态如何.
结论:
- 长期COVID似乎不会使个人对长时间坐着的感觉增加或通过LPA中断的益处减少.
- 在长时间坐着后,有和没有LC的个体都会经历类似的血压升高.
- 在这种情况下,轻微的体力活动中断并不能有效地缓解坐着引起的血压增加.
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