探索预防怀孕期间尿路感染的非抗生素干预措施:系统性审查
Shivani Srivastava1, Shreekar Roddam2, Deepshikha Srivastava3
1General Medicine, Stepping Hill Hospital, Stockport, GBR.
Cureus
|October 7, 2025
概括
非抗生素干预措施 (NAI),如蔓越和地中海饮食,可以帮助预防妊娠期间的尿路感染 (UTI),减少抗生素使用和抗菌素耐药性 (AMR). 需要更多的研究来证实有效性和安全性.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 药理学和药房 药理学和药房
背景情况:
- 尿路感染 (UTI) 在怀孕期间很常见,通常用抗生素治疗.
- 抗生素耐药性 (AMR) 是一个重要的公共卫生问题,主要是由于滥用抗生素.
- 非抗生素干预 (NAI) 为孕妇预防尿路感染提供了潜在的替代方案.
研究的目的:
- 系统地审查用于怀孕期间预防尿路感染的NAI.
- 评估国家药物协会在减少抗生素处方和打击AMR方面的潜力.
- 在英国国家卫生服务 (NHS) 护理系统的背景下评估国家卫生机构.
主要方法:
- 系统的文学搜索 欧维德·梅德林,科学网,和斯科普斯.
- 包括随机对照试验,队列研究和其他相关设计,将NAI与安慰剂,常规护理或没有干预进行比较.
- 由于干预的异质性,研究的质量评估和叙事合成.
主要成果:
- 八项研究符合纳入标准,调查了蔓越产品,地中海饮食,OM-89,甲酸和基于知识的干预措施.
- 来自七项研究的证据表明,NAI可能会减少尿路感染的发生率,但发现有限.
- 现有证据的低质量需要进一步的研究.
结论:
- 国标药物,特别是蔓越产品和地中海饮食,在减少怀孕期间尿路感染发病率方面表现有前途.
- 这些干预措施可能提供一种限制抗生素使用和减轻AMR的策略.
- 进一步进行高质量的研究是必要的,以确定在孕妇中使用NAI的安全性,有效性和成本效益.
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