相关实验视频
Updated: Jul 16, 2026

09:36
Measurement of Spatial Stability in Precision Grip
Published on: June 4, 2020
3.5K
弥合疼痛和运动认知风险综合征:手握强度的调解作用
Xiaojiang Zhao1, Yongguo Zhu2, Laiguo Han1
1Department of Physical Education and Arts, Bengbu Medical University, Bengbu, 233030, People's Republic of China.
Journal of pain research
|October 7, 2025
概括
运动认知风险综合征 (MCR) 与疼痛增加和手握强度 (HGS) 降低有关. HGS部分调解了疼痛和MCR之间的关系,突出了潜在的认知衰退干预目标.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 运动认知风险综合征 (MCR) 是痴呆症的临床前阶段.
- MCR预测了未来的认知恶化和痴呆症.
- 疼痛,手握强度 (HGS) 和MCR之间的联系需要进一步研究.
研究的目的:
- 调查慢性疼痛,HGS和MCR患病率之间的联系.
- 确定HGS是否调解疼痛和MCR之间的关系.
- 探索影响这些关联的人口因素.
主要方法:
- 2015年中国健康与退休纵向研究 (CHARLS) 数据的横截面分析.
- 包括没有被诊断为痴呆症的45岁以上的参与者.
- 后勤回归和调解分析以评估疼痛,HGS和MCR关系.
主要成果:
- 分析了4795名个人 (147例MCR病例) 的队列.
- 疼痛与MCR正相关 (OR=1.90),而HGS与MCR负相关 (OR=0.91).
- 在疼痛与MCR关系中,HGS介导了24.87%,具有显著的间接效应 (p < 0.001).
结论:
- 疼痛与MCR有积极的关联,而HGS与MCR有负面的关联.
- 在疼痛与MCR之间的关联中,HGS起着调解作用.
- 研究结果表明,潜在的治疗目标可以减轻MCR风险.
相关概念视频
Muscle Coordination and Action
Muscle coordination is a complex and finely tuned process essential for smooth and purposeful movements like flexion, extension, adduction, abduction, and rotation. The human body orchestrates the actions of various muscles working in concert, each with a specific role. Four functional types describe how muscles work together: agonist, antagonist, synergist, and fixator.
Agonists
Agonist muscles, often called prime movers, are the primary muscles responsible for producing a specific movement.
Agonists
Agonist muscles, often called prime movers, are the primary muscles responsible for producing a specific movement.
Analgesia and Pain Management
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Exercise and Cardiovascular Response
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

