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在骨骨折中局部注射的德克萨米他与没有维生素C的比较评估:一项随机对照试验

Anuja Chincholkar¹, B M Rudagi¹, Sneha Setiya²

¹Department of Oral and Maxillofacial Surgery, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra 411018 India.

Journal of maxillofacial and oral surgery

|October 7, 2025

概括

在下骨骨折手术后,在甲注射下下添加维生素C显著改善了软组织伤口愈合. 这种组合疗法提供了一种有希望的方法来减少并发症,并加强面创伤患者的康复.

科学领域:

口腔和牙面部外科手术
创伤管理创伤管理
伤口治愈研究研究伤口治愈研究

背景情况:

面创伤,特别是下副骨折,在印度是一个越来越大的挑战.
标准的开放缩减和内部固定可能会导致并发症.
局部皮质类固醇注射 (德甲) 可以减少术后,但有软组织脱落的风险;维生素C作为下替代品正在探索.

研究的目的:

为了评估和比较术后的伤口愈合,胀和疼痛.
评估单独使用德克萨米他松与使用德克萨米他松和维生素C组合治疗下副骨折的结果.

主要方法:

一项随机研究涉及30名下副骨折患者.
第1组接受了手术内肌肉内注射德克萨米他到头脑肌肉中.
第二组在线附近接受了膜下维生素C注射,同时接受了德克萨米他.

主要成果:

两组人都显著减少了面部胀和手术后疼痛.
与德克萨米他一起进行下维生素C的使用,与单独使用德克萨米他相比,导致软组织的伤口愈合更好.

结论:

维生素C增强了原蛋白的合成,抵消了德克萨的潜在软组织降解作用.
德克萨米他和维生素C的组合建议用于管理下副骨折,以改善伤口愈合和减少并发症.

关键词:

脸部的胀脸部的胀当地的皮质类固醇.口面部创伤口面部创伤维生素C注射剂维生素C注射剂伤口愈合伤口愈合

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