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对手术前/手术后抗生素治疗在减少第三骨摘取手术后手术并发症的有效性进行系统审查
Shahrokh Raiesian1, Amir Danial Pour Ahmadiyeh1, Mahdis Masoud Rad1
1Department of Oral and Maxillofacial Surgery, School of Dentistry, Ahvaz Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Journal of maxillofacial and oral surgery
|October 7, 2025
概括
在第三提取前或之后服用预防性抗生素并不能显著减少手术后的疼痛和胀. 牙医应该权衡抗生素的益处与细菌耐药性和副作用等风险.
科学领域:
- 牙科手术 牙科手术
- 药理学 药理学是指药理学的学科.
- 预防传染病 预防传染病
背景情况:
- 拔除第三牙是一种常见的牙科手术,经常伴有疼痛和胀.
- 预防性抗生素用于缓解手术后并发症,但研究结果是矛盾的.
- 抗生素的使用旨在预防感染并减少疼痛等临床症状.
研究的目的:
- 为了审查和比较抗生素的有效性,在第三提取之前与之后.
- 评估预防性抗生素对减少手术并发症的影响.
- 综合当前关于抗生素在第三取物中使用的证据.
主要方法:
- 自2000年以来发表的临床试验的系统审查.
- 在PubMed,Scopus,Web of Science和谷歌学者数据库中进行的搜索.
- 在选择相关研究时采用了包含和排除标准.
主要成果:
- 对18项研究的分析显示,没有统计学上显著的证据支持抗生素疗效.
- 抗生素没有明确地预防提取后的并发症,如疼痛和胀.
- 目前的证据不证实抗生素在第三提取过程中的常规益处.
结论:
- 牙医必须仔细考虑抗生素的风险,包括增加的细菌耐药性和潜在的副作用.
- 在某些病例中,使用抗生素的缺点可能会超过它的好处.
- 证据不支持常规预防性使用抗生素用于第三取物.
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