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Updated: Jan 15, 2026

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线粒体呼吸链通过 lysosomal 酸化的双调节来调节 HBV 清除

Zhiqiang Wei1, Yanying Yan1, Lingzhu Zhao1

  • 1State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People's Republic of China.

Emerging microbes & infections
|October 7, 2025
PubMed
概括

慢性乙型肝炎 (CHB) 损害了线粒体功能,导致溶酶体功能障碍和病毒复制增加. 这种功能障碍阻碍了身体清除乙型肝炎病毒 (HBV) 的能力.

关键词:
Lysosomal 降解 溶酶体的降解这是一个V-ATPase组件.乙型肝炎病毒的感染.溶酶体膜透性透化线粒体 - 溶酶体接触者线粒体的ATP合成这里是mtROSROS.

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