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Updated: Jan 15, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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在DNA损伤后,APOBEC3B在核细胞中对RNase H敏感的积累

Yohei Saito1, Yumi Yamamoto1, Fumihiko Yamamoto1

  • 1Division of Radiopharmacy, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Japan.

Bioscience reports
|October 7, 2025
PubMed
概括

阿波蛋白B mRNA编辑催化子单元3B (A3B) 在DNA损伤后积聚在细胞核中,与RNA螺旋酶相互作用. 这揭示了癌症中A3B诱导的DNA损伤的新机制,影响了遗传多样性.

关键词:
结合DNA的蛋白质可以结合DNA.对DNA损伤的反应反应在DNA拓酶中.突变发生的突变发生.核矩阵是一个核矩阵.核的核心是核的核.

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