血管病患者上肢截肢相关的死亡率:对9,904个个体的匹配队列分析
Nicholas C Bank1, Seong-Won Kim2, Bradley J Lauck2
1Department of Orthopaedics, University of North Carolina, Chapel Hill, NC; Case Western Reserve University School of Medicine, Department of Orthopaedics, Cleveland, OH.
周围血管疾病 (PVD) 增加了上肢截肢 (UEA) 患者的死亡风险. 这项研究发现,PVD患者在UEA后的死亡率高于没有PVD的患者.
科学领域:
- 血管外科 血管外科
- 患者的治疗结果.
- 死亡风险评估 死亡风险评估
背景情况:
- 周围血管疾病 (PVD) 是下肢截肢的已知危险因素,但其对上肢截肢的影响不太清楚.
- 评估接受UEA的血管病患者的死亡风险对于改善患者护理和治疗结果至关重要.
研究的目的:
- 确定与外周血管疾病 (PVD) 患者的上肢截肢 (UEA) 相关的死亡风险.
- 为了比较UEA接受PVD和没有PVD的患者之间的死亡率.
主要方法:
- 使用ICD-10和CPT代码对TriNetX数据库进行回顾性分析,以识别接受UEE的患者.
- 创建了两个队列:带有PVD的UEA和没有PVD的UEA,使用倾向得分进行1:1匹配.
- 使用Kaplan-Meier生存分析和相对风险计算来评估6个月,1年,5年和10年的死亡率.
主要成果:
- 这项研究包括了36368名患者,每个患者的队列均为4952名患者.
- 与PVD队列相比,在所有时间点中,没有PVD接受UEA的患者的死亡率显著降低.
- 在UEA后的每个测量间隔中,PVD组的死亡率更高.
结论:
- 患有外周血管疾病的患者的上肢截肢与死亡风险增加有关.
- 这些发现强调了在评估UEA患者的预后时考虑PVD状态的重要性.
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