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人工智能在内分泌实践中:比较ChatGPT,Gemini和Claude对上腺意外瘤的护理
Özge Baş Aksu1, Rıfat Furkan Aydın2, Asena Gökçay Canpolat3
1Department of Endocrinology and Metabolism, Ankara University School of Medicine, Ankara, Turkey. ozgebasaksu@gmail.com.
Journal of endocrinological investigation
|October 7, 2025
概括
大型语言模型 (LLM) 显示了对管理上腺瘤的承诺,在例行任务中表现相似,但在复杂的场景中有所不同. 仔细的模型选择和人类监督对于内分泌学有效的临床整合至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 人工智能的人工智能
- 医疗信息学 医疗信息学
背景情况:
- 人工智能 (AI) 的临床应用正在内分泌学中不断增长.
- 大型语言模型 (LLM) 对管理上腺瘤的有效性尚未得到充分证实.
研究的目的:
- 评估和比较四个LLM (ChatGPT-4o,ChatGPT-o1,Google Gemini 2.0,Claude 3.5) 在解决与上腺意外瘤相关的基于指南的查询和临床场景方面的表现.
主要方法:
- 一项横截面研究,涉及34个指导方针衍生的问题和四个案例场景,呈现给四个LLM.
- 六名内分泌学家使用利克尔特尺度对幻觉,质量,可用性,可靠性和准确性进行了评估.
- 分析了可读性指标和字数.
主要成果:
- 在诊断,治疗/随访和患者问题方面,在LLM中没有观察到显著的绩效差异.
- 在复杂的病例中,ChatGPT-4o表现优于ChatGPT-o1,特别是在幻觉控制,质量和可用性方面 (p < 0.05).
- 可读性分析表明,文本复杂度很高 (弗莱什-金凯德分级:10.6-17.4),评审者之间的可靠性很好 (ICC:0.876-0.961).
结论:
- 在管理上腺偶发性瘤方面,LLM具有作为决策支持工具的潜力.
- 虽然LLM的表现在常规任务中是相似的,但复杂的案例显示出显著的差异,强调需要明智的模型选择.
- 人类监督和关注LLM生成内容的可读性对于内分泌实践至关重要.
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