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超越BMI:中心肥胖度和晚年心血管风险
Onur Erdoğan1, Tuğba Erdoğan2, Neslihan Hazel Önür3
1Department of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
Aging clinical and experimental research
|October 7, 2025
概括
在老年人中,腰与部的比率 (WHR),腰与身高的比率 (WHtR) 和相对脂肪量 (RFM) 更好地预测缺血性心脏病 (IHD) 比体重指数 (BMI). 这些脂肪分布措施有助于评估心血管风险.
科学领域:
- 老年学是一门学科.
- 心血管医学 心血管医学
- 肥胖问题研究研究
背景情况:
- 与年龄相关的身体成分变化可能会降低老年人BMI等传统肥胖指标的准确性.
- "肥胖悖论"使得这个人口群体的心血管风险评估变得复杂.
- 像BMI这样的传统措施可能无法充分捕捉老年人群中的心血管风险.
研究的目的:
- 评估65岁及以上个体缺血性心脏病 (IHD) 的各种人类指数的预测能力.
- 为了比较不同的身体组成措施在评估老年人群IHD风险方面的有效性.
主要方法:
- 一项横截面的观察性研究,涉及1174名65岁以上的社区成年人.
- 人类指数的测量包括BMI,腰围 (WC),WHR,WHtR,BAI,RFM,身体脂肪百分比和骨肌肉质量.
- 使用多变量逻辑回归和ROC曲线分析来确定IHD的关联和歧视力.
主要成果:
- WHR,WHtR,WC和RFM独立地与IHD相关,而BMI,BAI和身体脂肪百分比没有.
- WHR (AUC=0.611),WHtR (AUC=0.561) 和RFM (AUC=0.555) 在IHD方面表现出显著的歧视性表现.
- 较高的WHR,WHtR,WC和RFM与老年人心血管疾病的几率增加有关.
结论:
- 像WHR,WHtR和RFM这样的中央肥胖度指标显示,与BMI相比,老年人中IHD的预测价值更高.
- 这些指数可能会增强心血管风险模型,但作为独立工具的区分能力有限.
- 这些发现支持将脂肪分布指数纳入老年人综合性心血管风险评估中.
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