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针对内体中的蛋白酶激活受体2的纳米药物提供持续的止痛作用

Shavonne L Teng1,2, Rocco Latorre1,2, Divya Bhansali3

  • 1Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.

Proceedings of the National Academy of Sciences of the United States of America
|October 7, 2025
PubMed
概括

纳米颗粒提供药物来对抗细胞内蛋白酶激活受体2 (PAR2) 信号,有效缓解疼痛并使临床前模型中的行为正常化. 这种纳米医学的方法显示了通过向G蛋白结合受体 (GPCRs) 来治疗各种疾病的前景.

关键词:
内分泌体内分泌体内分泌体内分泌体纳米颗粒是一种纳米粒子.疼痛 疼痛 疼痛 疼痛这些受体是受体受体.信号传导的信号传导.

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