准备为外科手术? 对麻醉提供者进行术后推的全面叙述审查
Jennifer R Majumdar1, Jake W Forrester2, Kelly S Haviland3
1Assistant Specialty Director, Nurse Anesthesia Adult Gerontology Acute Care DNP Program at Hunter College, City University of New York, New York, New York; a Nurse Scientist in the Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, New York
AANA journal
|October 7, 2025
概括
麻醉提供者应在手术期间继续进行暴露前预防 (PrEP) 以预防艾滋病毒. 了解 PrEP 的知识
科学领域:
- 麻醉学和外科手术期间的医学.
- 预防传染病 预防传染病
- 药理学 药理学是指药理学的学科.
背景情况:
- 暴露前预防 (PrEP) 用于预防艾滋病毒的使用量急剧增加,需要为麻醉提供者提供术后管理指南.
- 了解PrEP药物的影响至关重要,因为这些方案中的患者越来越多地接受手术.
研究的目的:
- 对使用PrEP的患者进行术后考虑的当前文献进行审查.
- 为麻醉提供者提供基于证据的建议,以优化患者安全和结果.
主要方法:
- 从2013年到2024年进行全面的文献搜索,重点关注PREP药理学,副作用和术后影响.
- 对当前PrEP配方的分析:特鲁瓦达,德斯科维和阿普雷图德.
主要成果:
- 基于tenofovir的PrEP可能会增加毒性风险,特别是在NSAIDs.
- 埃姆特里西塔宾/特诺福维尔阿拉芬胺与高血压和高胆固醇血症有关.
- 没有任何麻醉剂是禁忌的,但可能需要对脏药物剂量进行调整.
结论:
- 在整个外科手术后期继续使用PrEP得到了当前证据的支持.
- 麻醉提供者必须将安全的患者护理与艾滋病毒预防工作相结合.
- 建议进一步研究PrEP的长期麻醉作用和最佳的术后管理.
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