对特定领域的体力活动和久坐行为与腹腔大动脉化风险的剂量-反应和同位时间替代分析:一个横截面研究
Zhuohui Yang1, Lin Zhu1,2,3, Zekai Chen1
1School of Exercise and Health, Guangzhou Sport University, Guangzhou, China.
PloS one
|October 7, 2025
概括
增加休时间的体力活动和减少久坐行为可以降低腹腔大动脉化 (AAC) 的风险. 休时间中度至强度的体力活动 (MVPA) 显示出保护作用,而久坐行为增加了AAC风险.
科学领域:
- 心血管健康 心血管健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 腹腔大动脉化 (AAC) 是心血管疾病的重要独立风险因素.
- 了解身体活动,久坐行为和AAC之间的关系对于预防策略至关重要.
研究的目的:
- 为了研究不同类型的中度至强度体力活动 (MVPA) 和久坐行为 (SB) 与AAC风险之间的剂量反应关系.
- 分析这些行为之间重新分配时间对40岁及以上成年人AAC风险的影响.
主要方法:
- 使用NHANES 2013-2014年数据进行的横截面研究.
- 自报的MVPA和SB,AAC通过Kauppila评分和DXA进行评估.
- 权重后勤回归与受限制的立方线和同位时间替代分析.
主要成果:
- 遵守休时间MVPA指南显著降低了AAC风险 (OR=0.643).
- 剂量反应分析显示,MVPA总量的U形关联,以及休时间MVPA和SB的线性关联.
- 将SB或职业MVPA替换为休时间的MVPA降低了AAC风险.
结论:
- 久坐不动的行为与AAC风险有积极的关联,而休时间的MVPA与AAC风险有负面的关联.
- 在1086分钟/周的总MVPA时观察到最佳的AAC风险降低.
- 从SB或职业MVPA转移时间到休时间的MVPA是降低AAC风险的可行策略.
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