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TCN-RDP:从时间序列毒基因组数据预测药物诱导的肝损伤

Zhongyan Zhao1, Bin Li2, Haochen Zuo1

  • 1College of Intelligence and Computing, Tianjin University, Tianjin 300350, China.

Journal of chemical information and modeling
|October 7, 2025
PubMed
概括

一个新的模型,TCN-RDP,使用基因表达数据准确预测药物诱导的肝损伤 (DILI). 这种计算方法提高了早期药物安全性评估,并减少了临床试验失败.

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