睡眠障碍对血管认知障碍认知变化的贡献
Jiaqi Luo1, Fei Li2, Pengjun Zhao3
1Department of Traditional Chinese Medicine, Putuo District Central Hospital, Shanghai, 200062, China.
Sleep medicine
|October 7, 2025
概括
失眠和睡眠呼吸暂停等睡眠障碍在脑血管疾病中很常见,并与认知能力下降有关. 解决这些睡眠问题可能有助于管理血管认知障碍 (VCI).
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 认知科学 认知科学
背景情况:
- 血管认知障碍 (VCI) 是一个重大的全球健康挑战,增加了残疾和死亡率.
- 早期识别和管理可修改的风险因素对于减轻VCI的影响至关重要.
- 睡眠障碍越来越多地被认为是脑血管疾病和认知障碍的潜在贡献者.
研究的目的:
- 系统地审查和综合现有关于睡眠障碍和脑血管疾病患者认知障碍之间的关联的研究.
- 为了确定特定的认知领域容易受到睡眠障碍的影响在这个人群中.
- 为VCI的早期发现,监测和管理策略提供信息.
主要方法:
- 按照PRISMA指南进行了系统审查.
- 在主要的数据库中进行了搜索:PubMed,Embase,Web of Science,Scopus和Cochrane Central.
- 包括专注于人类受试者的研究,调查睡眠障碍与脑血管疾病中的认知障碍之间的联系.
主要成果:
- 分析了12项涉及5525名参与者的研究.
- 常见的睡眠障碍包括呼吸相关睡眠障碍 (BSD),失眠,过度白天嗜睡 (EDS) 和周期性四肢运动障碍 (PLMD).
- 阻塞性睡眠呼吸暂停 (OSA),睡眠碎片化和改变的总睡眠时间 (TST) 与一般认知和特定领域 (如记忆,执行功能和注意力) 的缺陷有关.
结论:
- 睡眠障碍在患有脑血管疾病的个体中非常普遍.
- 各种睡眠障碍 (例如,OSA,失眠) 和认知障碍之间存在显著的关联,影响多个认知领域.
- 这些发现强调了睡眠健康在VCI的背景下的重要性,并建议睡眠评估作为管理的关键组成部分.
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