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墨西哥登革热的流行病学和经济负担:2010年至2020年的数据分析
Victoria Pando-Robles1, Julio Alvarez-Obregón2, Guadalupe Díaz Del Castillo-Flores3
1Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Morelos, Mexico.
The American journal of tropical medicine and hygiene
|October 7, 2025
概括
墨西哥的登革热监测显示,住院死亡率显著增加,严重登革热病例在年轻人群中发生转变. 伴随性疾病和怀孕增加了死亡风险,强调了有针对性的干预措施的必要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 卫生经济学 卫生经济学
背景情况:
- 登革热是全球主要的树状病毒病,对公共卫生和经济产生重大影响.
- 了解登革热的负担,包括相关的风险因素和成本,对于有效的疾病管理至关重要.
研究的目的:
- 确定2010年至2020年墨西哥登革热的流行病学和经济负担.
- 确定与严重的临床结果和医疗保健资源利用相关的并发症和疾病.
主要方法:
- 从国家数据库 (Sistema Nacional de Vigilancia Epidemiológica和Sistema Único de Información para la Vigilancia Epidemiológica) 获得的登革热监测数据的回顾性分析.
- 包括可能,确诊,门诊,住院病例,死亡,并发病,怀孕状态和医疗保健资源利用数据.
- 分析住院死亡率,年龄分布的变化以及疫情期间和疫情之外的经济成本.
主要成果:
- 超过160万例登革热病例被记录,超过11万例住院治疗和1385例死亡.
- 住院死亡率从0.72%增加到2.6%;严重的登革热病例转移到年轻年龄组 (0-19岁).
- 伴随性疾病 (糖尿病,肝硬化,高血压,病,血液学疾病),怀孕和胃潰瘍与增加住院和死亡风险有关. 疫情期间的年度医疗费用超过1.11亿美元.
结论:
- 登革热在墨西哥造成了巨大的和日益增加的负担,其特点是死亡率上升和受严重疾病影响的年轻人群.
- 特定的并发病和怀孕状态显著提高了严重登革热结果的风险,需要量身定制的公共卫生策略.
- 经济影响,特别是在疫情爆发期间,强调需要强有力的监测和特定年龄的干预措施,以减轻登革热的负担.
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